How to Read Hsv 2 Test Results

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Synonyms

Canker-ii
HSV Type 2-Specific Antibody, IgG
HSV-2

Special Instructions

If patient outcome falls betwixt 0.91 (Equivocal) and five.00 (Low Positive) Alphabetize values, the specimen will reflex to 163006 HSV-2 Supplemental test per CDC guidelines.

If reflex exam is performed, additional charges/CPT lawmaking(s) may use.

Expected Turnaround Time

i - 3 days

Turnaround time is defined every bit the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional fourth dimension should be immune for additional confirmatory or additional reflex tests. Testing schedules may vary.

Specimen Requirements

Specimen

Volume

Minimum Volume

Container

Red-top tube, gel-bulwark tube, or serum transfer tube

Storage Instructions

Stability Requirements

Temperature	Flow
Room temperature	two days
Refrigerated	7 days
Frozen	98 days
Freeze/Thaw Bicycle	Stable x4

Causes for Rejection

Hemolysis; lipemia; grossly icteric; visible particulate matter; gross bacterial contamination

Test Details

Utilise

Detect IgG antibodies specific to HSV type 2 infection; confirm or rule out possible infection with herpes simplex type 2 virus in prenatal patients in whom HSV two infection can crusade serious prenatal affliction. Per CDC guidelines, specimens with equivocal or low positive results for HSV-ii type specific IgG will reflex for supplemental testing past another assay.

In a patient with no history of lesion disease, a positive result for this test may be indicative that the primary infection was asymptomatic. The magnitude of the Index Value is non indicative of the amount of antibody present in the patient sample. One time infected by HSV, it is possible for a patient to shed virus without the development of lesions (asymptomatic shedding). This test does non point the site of HSV infection. There is a considerable homology between HSV-1 and HSV-2 antigens, and so that antibodies formed against either virus are highly cross-reactive. This assay is based on glycoprotein Chiliad-2, purified from HSV-2 infected cells, and is specific for blazon 2 antibodies.

HSV-2 IgG Type Specific	HSV-2 IgG Supplemental	Estimation
Positive / Equivocal	Positive	Indicates the presence of detectable IgG antibodies to HSV-two.
Positive / Equivocal	Negative	Unable to ostend the presence of IgG antibodies to HSV-ii. Recommend retesting in 2 to 4 weeks.

Limitations

This test is intended for qualitative determination simply. The magnitude of the Index Value is not indicative of the amount of antibody present in the patient sample.

Methodology

Chemiluminescent immunoassay (CLIA). Reflex of specimens equivocal and low positive for HSV-2 type specific IgG to a membrane based immunoassay.

Additional Data

Set upward Monday thru Fri.

References

Ashley R, Cent A, Maggs V, Nahmias A, Corey L. Inability of enzyme immunoassays to discriminate betwixt infections with herpes simplex virus types 1 and 2. Ann Intern Med. 1991 Oct 1; 115(7):520-526.1652909

Centers for Disease Command and Prevention. Sexually-transmitted disease treatment guidelines 2002. MMWR. 2002; 51(RR-6).12184549

Corey L. The current trend in genital herpes. Progress in prevention. Sex activity Transm Dis. 1994 Mar-Apr; 21(2 Suppl):S38-S44.8042114

Whitley RJ. Herpes simplex infections of women and their offspring: Implications for a developed society. Proc Natl Acad Sci USA. 1994 Mar 29; 91(7):2441-2447 (review).8146137

LOINC® Map

Social club Code	Order Code Name	Order Loinc	Outcome Code	Result Code Name	UofM	Outcome LOINC
163033	HSV-2 Blazon Spec Ab, IgG w/Rflx	5209-2	163034	HSV 2 IgG, Type Spec	index	5209-2

Reflex Table for HSV 2 IgG, Blazon Spec
	Lodge Code	Order Name	Event Code	Consequence Proper noun	UofM	Result LOINC
Reflex 1	163006	HSV-2 IgG Supplemental Exam	163013	HSV-2 IgG Supplemental Test		43180-9

CPT Argument/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Constitute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, re-create, or distribute the LOINC® codes for any commercial or not-commercial purpose, subject field to the terms under the license agreement found at https://loinc.org/license/. Additional data regarding LOINC® codes can exist plant at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf

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Source: https://www.labcorp.com/tests/163033/herpes-simplex-virus-hsv-type-2-specific-antibodies-igg-with-reflex-to-supplemental-testing

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